The berberine HCL component of this supplement is known for its free-radical fighting activity, immune system support, and proper microbial balance. It also helps activate AMPK, also known as the body's metabolic master switch. NutriFlair Berberine with Organic Ceylon Cinnamon is suitable for vegetarians and vegans, and is non-GMO, gluten-free and dairy-free. Amin AH, Subbaiah TV, Abbasi KM. Berberine sulfate: antimicrobial activity, bioassay, and mode of action. Can J Microbiol 1969;15:1067-76. View abstract. Berberine is a plant alkaloid with powerful antioxidant properties, and taking this dietary supplement once a day can help to reduce the negative side effects of an unhealthy diet and improve overall well-being. Trimarco, V., Cimmino, C. S., Santoro, M., Pagnano, G., Manzi, M. V., Piglia, A., Giudice, C. A., De, Luca N., and Izzo, R. Nutraceuticals for blood pressure control in patients with high-normal or grade 1 hypertension. High Blood Press Cardiovasc.Prev. 9-1-2012;19(3):117-122. View abstract.

Tripathi YB and Shukla SD. Berberis artistata inhibits PAF induced aggregation of rabbit platelets. Phytotherapy Research 1996;10:628-630.Doctor Recommended Supplements Berberine with Ceylon Cinnamon is made in the USA in a registered laboratory that meets cGMP standards and is all natural, free of soy, gluten, milk, egg, wheat, GMOs, peanuts, sweeteners, shellfish and sugar. When looking for a brand of organic berberine supplement, there are a few key points to consider that can help you make an informed decision. We just have to wait sometimes for research to catch up. But research requires money. And research requires time.” Kim, W. S., Lee, Y. S., Cha, S. H., Jeong, H. W., Choe, S. S., Lee, M. R., Oh, G. T., Park, H. S., Lee, K. U., Lane, M. D., and Kim, J. B. Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity. Am J Physiol Endocrinol.Metab 2009;296(4):E812-E819. View abstract.

Seow WK, Ferrante A, Summors A, and et al. Comparative effects of tetrandrine and berbamine on production of the inflammatory cytokines interleukin-1 and tumor necrosis factor. Life Sciences 1992;50(8):pl-53-pl-58. Zhu B and Ahrens FA. Effect of berberine on intestinal secretion mediated by Escherichia coli heat-stable enterotoxin in jejunum of pigs. Am J Vet Res 1982;43(9):1594-1598. As with any supplement, it’s best not to take any berberine until you’ve talked with a member of your health care team, especially as berberine may interact with other medications or supplements. Definitely don’t drop a prescription drug such as metformin in favor of berberine without talking to your prescribing doctor or a pharmacist.

Hot Products

Kaneda Y, Tanaka T, and Saw T. Effects of berberine, a plant alkaloid, on the growth of anaerobic protozoa in axenic culture. Tokai J Exp Clin Med 1990;15(6):417-423. Berberine HCL (Berberis Aristata) is a compound found in plants such as barberry and goldenseal that can help regulate and support immune function, gastrointestinal support, promote weight management and cardio health. Organic Ceylon Cinnamon (Cinnamomum verum, Bark) is sourced directly from Sri Lanka and known for its distinctive shape and lighter color. It also has antioxidant properties to help support immune function and promote health. May Promote Weight Loss. Research has also uncovered that berberine reduces adipocyte (fat cell) growth by regulating the activity of specific genes involved in that process. In a study with mildly overweight adults, people who supplemented with berberine for one month lost weight and had increased brown adipose tissue activity—also known as brown fat, this healthy type of fat tissue is more metabolically active and increases energy expenditure. Wu, H. L., Hsu, C. Y., Liu, W. H., and Yung, B. Y. Berberine-induced apoptosis of human leukemia HL-60 cells is associated with down-regulation of nucleophosmin/B23 and telomerase activity. Int J Cancer 6-11-1999;81(6):923-929. View abstract. Iizuka, N., Oka, M., Yamamoto, K., Tangoku, A., Miyamoto, K., Miyamoto, T., Uchimura, S., Hamamoto, Y., and Okita, K. Identification of common or distinct genes related to antitumor activities of a medicinal herb and its major component by oligonucleotide microarray. Int J Cancer 11-20-2003;107(4):666-672. View abstract.

Huang, W. [Ventricular tachyarrhythmias treated with berberine]. Zhonghua Xin.Xue.Guan.Bing.Za Zhi. 1990;18(3):155-6, 190. View abstract. Chatterjee P, Franklin MR. Human cytochrome p450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components. Drug Metab Dispos 2003;31:1391-7. View abstract. Ruscica M, Gomaraschi M, Mombelli G, Macchi C, Bosisio R, Pazzucconi F, Pavanello C, Calabresi L, Arnoldi A, Sirtori CR, Magni P. Nutraceutical approach to moderate cardiometabolic risk: results of a randomized, double-blind and crossover study with Armolipid Plus. J Clin Lipidol. 2014;8(1):61-8. View abstract. Organic Vitality Berberine HCL is easy to swallow, as the small and soft methylcellulose capsules are tasteless. Plus, they are 100% vegan friendly, so you can take this supplement with confidence. Our Berberine is made in the USA in a registered and inspected facility that is (GMP) compliant.

Berberine Other Benefits

Dong H, Zhao Y, Zhao L, Lu F. The effects of berberine on blood lipids: a systemic review and meta-analysis of randomized controlled trials. Planta Med 2013;79(6):437-46. View abstract. Pisciotta, L., Bellocchio, A., and Bertolini, S. Nutraceutical pill containing berberine versus ezetimibe on plasma lipid pattern in hypercholesterolemic subjects and its additive effect in patients with familial hypercholesterolemia on stable cholesterol-lowering treatment. Lipids Health Dis 2012;11:123. View abstract. Marazzi G, Pelliccia F, Campolongo G, Quattrino S, Cacciotti L, Volterrani M, et al. Usefulness of nutraceuticals (Armolipid Plus) versus ezetimibe and combination in statin-intolerant patients with dyslipidemia with coronary heart disease. Am J Cardiol. 2015 Dec 15;116(12):1798-801. doi: 10.1016/j.amjcard.2015.09.023. View abstract. Kim, H. S., Kim, M. J., Kim, E. J., Yang, Y., Lee, M. S., and Lim, J. S. Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression. Biochem.Pharmacol 2-1-2012;83(3):385-394. View abstract. Ming J, Yu X, Xu X, et al. Effectiveness and safety of Bifidobacterium and berberine in human hyperglycemia and their regulatory effect on the gut microbiota: a multi-center, double-blind, randomized, parallel-controlled study. Genome Med 2021;13(1):125. View abstract.

Nutrivein's Premium Berberine HCL 1200mg Plus Organic Ceylon Cinnamon capsules offer a powerful combination of health benefits that can help to support glucose metabolism and overall well-being. Each serving delivers 1200mg of Berberine and 200mg of Organic Ceylon Cinnamon.You may notice that obesity didn’t make the shortlist. That’s because there aren’t enough high-quality studies on the subject, though there has been some research showing that berberine supplementation may help reduce weight. What are the risks of berberine? Pérez-Rubio KG, González-Ortiz M, Martínez-Abundis E, Robles-Cervantes JA, Espinel-Bermúdez MC. Effect of berberine administration on metabolic syndrome, insulin sensitivity, and insulin secretion. Metab Syndr Relat Disord 2013;11(5):366-9. View abstract. Chan M, Qin Z, Man SC, et al. Adjunctive berberine reduces antipsychotic-associated weight gain and metabolic syndrome in patients with schizophrenia: a randomized controlled trial. Psychiatry Clin Neurosci 2022;76(3):77-85. View abstract. Marazzi, G., Cacciotti, L., Pelliccia, F., Iaia, L., Volterrani, M., Caminiti, G., Sposato, B., Massaro, R., Grieco, F., and Rosano, G. Long-term effects of nutraceuticals (berberine, red yeast rice, policosanol) in elderly hypercholesterolemic patients. Adv.Ther 2011;28(12):1105-1113. View abstract. Taking berberine supplements regularly appears to lower total cholesterol, “bad” cholesterol, and triglycerides in people with high cholesterol. It works differently from today’s standard cholesterol medications, so it may help treat people who are resistant to other cholesterol-lowering drugs.