Solgar Inositol 500 mg Vegetable Capsules - Vitamin B8 - Vegan, Vegetarian, Kosher, 50 Count (Pack of 1)

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Fraticelli F, Celentano C, Zecca IA, et al. Effect of inositol stereoisomers at different dosages in gestational diabetes: an open-label, parallel, randomized controlled trial. Acta Diabetol. 2018;55(8):805-812. View abstract. Papaleo E, Unfer V et al. Myo-inositol in patients with polycystic ovary syndrome: a novel method for ovulation induction. Gynecol Endocrinol. 2007 Dec; 23(12):700-3. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. View abstract. What is the best myo-inositol supplement for fertility? Myo-inositol is a commodity supplement. Most brands should be capable of delivering similar clinical results. But independent studies have observed significant issues with product quality and labeling accuracy [ 62]. It’s advised to only use trusted suppliers like those mentioned above. A PCOS diet improves insulin sensitivity by reducing inflammation. You can achieve this by avoiding certain foods like sugar, gluten, and dairy. A PCOS diet also takes a direct approach to insulin regulation through a better balance of macronutrients. The Bottom Line

In a 2017 review on using inositols in PCOS, and published in Gynecological Endocrinology, the authors found combined treatment with myo-inositol and d-chiro inositol to be effective in restoring ovary function and metabolic balance in PCOS. 25 Weight - Santamaria A, Giordano D, Corrado F, Pintaudi B, Interdonato ML, Vieste GD, Benedetto AD, D'Anna R One-year effects of myo-inositol supplementation in postmenopausal women with metabolic syndrome Climacteric. (2012 Oct) Anxiety Symptoms - Gelber D, Levine J, Belmaker RH Effect of inositol on bulimia nervosa and binge eating Int J Eat Disord. (2001 Apr)Fertility - Unfer V, Carlomagno G, Rizzo P, Raffone E, Roseff S Myo-inositol rather than D-chiro-inositol is able to improve oocyte quality in intracytoplasmic sperm injection cycles. A prospective, controlled, randomized trial Eur Rev Med Pharmacol Sci. (2011 Apr) Kofman O, Einat H, Cohen H, Tenne H, Shoshana C The anxiolytic effect of chronic inositol depends on the baseline level of anxiety. J Neural Transm (Vienna). (2000) Genazzani AD, Lanzoni C et al. Myo-inositol administration positively affects hyperinsulinemia and hormonal parameters in overweight patients with polycystic ovary syndrome. Gynecol Endocrinol. 2008 Mar;24(3):139-44.
15. Minozzi M, Costantino D et al. The effect of a combination therapy with myo-inositol and a combined oral contraceptive pill versus a combined oral contraceptive pill alone on metabolic, endocrine, and clinical parameters in polycystic ovary syndrome. Gynecol Endocrinol. 2011 Nov;27(11):920-4.

Chatree S, Thongmaen N, Tantivejkul K, Sitticharoon C, Vucenik I Role of Inositols and Inositol Phosphates in Energy Metabolism. Molecules. (2020-Nov-01) Tagliaferri V, Romualdi D, Immediata V, et al. Metformin vs myo-inositol: which is better in obese polycystic ovary syndrome patients? A randomized controlled crossover study. Clin Endocrinol (Oxf). 2017;86(5):725–30. 10.1111/cen.13304 Glycemic Control - Wei J, Yan J, Yang H Inositol Nutritional Supplementation for the Prevention of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. (2022-Jul-09) Hallman M, et al. Inositol supplementation in premature infants with respiratory distress syndrome. N Engl J Med 1992;326:1233-9. View abstract.E.J., et al., Voluntary fortification is ineffective to maintain the vitamin B12 and folate status of older Irish adults: evidence from the Irish Longitudinal Study on Ageing (TILDA). Br J Nutr, 2018. 120(1): p. 111-120. S., et al., Inositols: From Established Knowledge to Novel Approaches. Int J Mol Sci, 2021. 22(19).

Anna, R., et al., Myo-inositol may prevent gestational diabetes in PCOS women. Gynecol Endocrinol, 2012. 28(6): p. 440-2. Fertility - Lisi F, Carfagna P, Oliva MM, Rago R, Lisi R, Poverini R, Manna C, Vaquero E, Caserta D, Raparelli V, Marci R, Moscarini M Pretreatment with myo-inositol in non polycystic ovary syndrome patients undergoing multiple follicular stimulation for IVF: a pilot study Reprod Biol Endocrinol. (2012 Jul 23) Depression Symptoms - Levine J, Barak Y, Gonzalves M, Szor H, Elizur A, Kofman O, Belmaker RH Double-blind, controlled trial of inositol treatment of depression Am J Psychiatry. (1995 May) Monastra G, Unfer V, Harrath AH, et al. Combining treatment with myo-inositol and D-chiro-inositol (40:1) is effective in restoring ovary function and metabolic balance in PCOS patients. Gynecol Endocrinol. 2017;33(1):1–9.Colodny L, Hoffman RL. Inositol--clinical applications for exogenous use. Altern Med Rev 1998;3:432-47. View abstract.